Code & Software

Open-source tools for meta-analysis, psychometrics, and patient-reported outcomes research.

R Packages

metaMultiverse

An R package for conducting multiverse meta-analyses.

Features:

  • 11+ meta-analytic methods (Fixed-effects, REML, PET-PEESE, p-uniform*, RVE, and more)
  • E/U/N decision framework for defining analytical specifications
  • Specification curves and Vibration of Effects (VoE) plots
  • Full test coverage and documentation

Installation:

# Install from GitHub
devtools::install_github("cyplessen/metaMultiverse")

Resources: GitHub · Getting Started Vignette

Related Publication: Plessen et al. (2024). Digital mental health interventions for the treatment of depression: A multiverse meta-analysis. Journal of Affective Disorders, 369, 1031-1044.

lordifMultiverse

An R package for detecting differential item functioning (DIF) using logistic regression in a multiverse analysis approach.

Features:

  • Logistic regression-based DIF detection
  • Test multiple criteria and thresholds simultaneously
  • Warning handling during DIF detection
  • Visualization of flagged items across methods

Installation:

# Install from GitHub
devtools::install_github("cyplessen/lordifMultiverse")

Resources: GitHub · Documentation

Shiny Applications

Patient-Specific PROMIS Reference Values

A web application for obtaining patient-specific reference values for PROMIS Physical Functioning, Upper Extremity, and Pain Interference item banks in general populations from the USA, UK, and Germany. Enter patient information (age, sex, country) to obtain personalized plots and reference values.

Features:

  • Visual “people plots” showing percentile rankings
  • Patient-specific reference tables
  • Compare patient scores to demographically-matched reference groups
  • Based on data from USA, UK, and Germany

Launch: Open App · Source Code

Related Publication: Plessen et al. (2023). How are age, gender, and country differences associated with PROMIS physical function, upper extremity, and pain interference scores? Clinical Orthopaedics and Related Research, 482(2), 244-256.

metaMultiverse Interactive Explorer

An interactive web application for conducting multiverse meta-analyses. Upload your data, define analytical decisions, and explore how different specifications affect your conclusions through interactive visualizations.

Features:

  • Step-by-step guided workflow
  • Interactive specification curve plots
  • Vibration of Effects (VoE) visualizations
  • Export results and plots
  • Built-in example datasets

Launch: Open App · Source Code

Related Publication: Plessen et al. (2024). Digital mental health interventions for the treatment of depression: A multiverse meta-analysis. Journal of Affective Disorders, 369, 1031-1044.